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Original Research
Online Published: 03 Oct 2018
 


EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM

AVVARU JAI VENKATA SAI PRASAD; RATNA MANIKYAM BATTU; B.N. UPADHYAYA; A. C. KAR;.


Abstract
Background - Tamaka shvasa mentioned in Ayurvedic classics is equated with bronchial asthma. Eosinophilia is normally observed in bronchial asthma patients with range of 500 to 2000 eosinophils /μl in blood. Eosinophils are able to produce many mediators responsible for inflammatory reaction. Safer herbal formulation having anti eosinophilic effect is required to decrease the Eosinophil circulation in peripheral blood.
Material and Method - Twelve freshly diagnosed cases of bronchial asthma having the eosinophil percentage between 5-24% and absolute eosinophil count between 540-1700/μlwere selected for the study. An Ayurvedic compound containing Sati (Hedychium spicatium Rose), Puskaramoola (Inula racemosa Linn) and Amalaki (Emblica officinalis Linn)was administered orally in dose of 9 grams in three divided doses in powdered form along with honey. Assessment was made on the basis of Eosinophil percentage and absolute eosinophil count.
Result - On treatment for 6 weeks with the trial drug, the mean percentage of eosinophil was 6, 4.25 and 2.16 was decreased to 5.6, 7.25 and 9.33 after 2, 4, and 6 weeks respectively which shows highly significant effect ((<0.001). The mean absolute count (AEC) before treatment was 942.1±136.9 which declined to 582.8, 375.5 and 218.3 at 2, 4, and 6 weeks respectively.
Conclusion - The results of the clinical study confirmed the anti-eosinophilic effect of the Sati, Puskara and Amalakichoorna which further supports the fact that it is a safe formulation for the treatment of eosinophilia in bronchial asthma.

Key words: Amalaki compound; Anti eosinophilic effect; Bronchial asthma; Eosinophilia; Sati Puskaramoola; Tamaka Shvasa;


 
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How to Cite this Article
Pubmed Style

PRASAD AJVS, BATTU RM, UPADHYAYA B, KAR AC, . EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. J Res Educ Indian Med . Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520

Web Style

PRASAD AJVS, BATTU RM, UPADHYAYA B, KAR AC, . EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. https://www.jreim-ayushjournal.com/?mno=294053 [Access: September 12, 2024]. doi:10.5455/JREIM.82-1521285520

AMA (American Medical Association) Style

PRASAD AJVS, BATTU RM, UPADHYAYA B, KAR AC, . EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. J Res Educ Indian Med . Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520


Vancouver/ICMJE Style

PRASAD AJVS, BATTU RM, UPADHYAYA B, KAR AC, . EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. J Res Educ Indian Med , [cited September 12, 2024]; Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520


Harvard Style

PRASAD, A. J. V. S., BATTU, . R. M., UPADHYAYA, . B., KAR, . A. C. & (0) EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. J Res Educ Indian Med , Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520


Turabian Style

PRASAD, AVVARU JAI VENKATA SAI, RATNA MANIKYAM BATTU, B.N. UPADHYAYA, A. C. KAR, and . 0. EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. Journal of Research and Education in Indian Medicine, Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520


Chicago Style

PRASAD, AVVARU JAI VENKATA SAI, RATNA MANIKYAM BATTU, B.N. UPADHYAYA, A. C. KAR, and . "EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM." Journal of Research and Education in Indian Medicine Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520


MLA (The Modern Language Association) Style

PRASAD, AVVARU JAI VENKATA SAI, RATNA MANIKYAM BATTU, B.N. UPADHYAYA, A. C. KAR, and . "EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM." Journal of Research and Education in Indian Medicine Online First: 03 Oct, 2018. Web. 12 Sep 2024 doi:10.5455/JREIM.82-1521285520


APA (American Psychological Association) Style

PRASAD, A. J. V. S., BATTU, . R. M., UPADHYAYA, . B., KAR, . A. C. & (0) EVALUATION OF AN AYURVEDIC COMPOUND OF H. SPICATUM, I. RACEMOSA AND E. OFFICINALIS FOR TREATMENT OF EOSINOPHILIA IN BRONCHIAL ASTHM. Journal of Research and Education in Indian Medicine, Online First: 03 Oct, 2018. doi:10.5455/JREIM.82-1521285520


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