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AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME

Manish V Patel, Kalapi B Patel, S N Gupta.

Abstract
BACKGROUND: Primary nephrotic syndrome is responsible for 12% of the causes of chronic kidney disease and up to 20% of ESRD. Patients often require cortico-steroids to get remission, yet many patients either show relapses after remission or do not respond to it. The better alternative is, however far from established.
OBJECTIVES: This study was performed to determine the effectiveness of the multi-modal Ayurvedic treatment in the patients of nephrotic syndrome.
MEHTODS: This is an observational study on 20 patients, performed with vardhamana pippali first 2 weeks followed by mild virechana karma with erandasneha. After virecana, patients were treated with oral Ayurvedic preparations for next 2 weeks. Patients were kept on Ayurvedic preparations except pippali for one year. Cortico-steroids (prednisolone) and immunosuppressive drugs (Cyclosporin) were stopped within the main assessment period. Patients were assessed symptomatically and on the basis of laboratory investigations i.e. serum albumin, serum cholesterol and albuminuria after completion of 4 weeks treatment. Patients were assessed every 2 months as follow up with a final assessment after the 12 months follow-up period.
RESULTS: Serum albumin was increased by 12.78% while total cholesterol level was decreased by 18.56%. Albuminuria was increased after the 4 weeks treatment may be because of discontinuation of steroids. However it was decreased by 80.28% after the 12 months follow-up without consumption of steroids or immunosuppressive drugs. These changes were statistically significant. Symptomatic betterment was also observed during the follow-up period. No any unwanted effects noted during the study period.

Key words: Primary nephrotic syndrome; Vardhamana pippali; Virechana karma


 
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Pubmed Style

Patel MV, Patel KB, Gupta SN. AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. doi:10.5455/JREIM.82-1422092361


Web Style

Patel MV, Patel KB, Gupta SN. AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. http://www.jreim-ayushjournal.com/?mno=178332 [Access: February 20, 2018]. doi:10.5455/JREIM.82-1422092361


AMA (American Medical Association) Style

Patel MV, Patel KB, Gupta SN. AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. doi:10.5455/JREIM.82-1422092361



Vancouver/ICMJE Style

Patel MV, Patel KB, Gupta SN. AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. doi:10.5455/JREIM.82-1422092361



Harvard Style

Patel, M. V., Patel, K. B. & Gupta, S. N. (0) AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. doi:10.5455/JREIM.82-1422092361



Turabian Style

Patel, Manish V, Kalapi B Patel, and S N Gupta. 0. AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. doi:10.5455/JREIM.82-1422092361



Chicago Style

Patel, Manish V, Kalapi B Patel, and S N Gupta. "AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME." doi:10.5455/JREIM.82-1422092361



MLA (The Modern Language Association) Style

Patel, Manish V, Kalapi B Patel, and S N Gupta. "AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME." doi:10.5455/JREIM.82-1422092361



APA (American Psychological Association) Style

Patel, M. V., Patel, K. B. & Gupta, S. N. (0) AYURVEDIC MANAGEMENT OF PRIMARY NEPHROTIC SYNDROME. doi:10.5455/JREIM.82-1422092361



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The articles in Journal of Research and Education in Indian Medicine (Estt.1982) are open access articles licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-sa/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.