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Original Research
Online Published: 17 Jun 2015
 


PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA.


Abstract
Cassine albens (R.) Kosterm belongs to the family celastraceae which is the rich
source of triterpenes and alkaloids. In present study hydroalcoholic extract of stem bark of Cassine
albens was investigated for antidepressant and anxiolytic activity in rodents. The dose dependant
study was performed at the doses of 100, 200, 400 and 800 mg/kg, p.o. Cassine albens showed
significant antidepressant activity in forced swim and tail suspension test. We observed significant
anxiolytic effect at the dose of 400 and 800 mg/kg, p.o. in elevated plus maze and marble burying
test in rodents. The present study substantiates folkloric use of Cassine albens in the treatment
of psychosomatic disorders.

Key words: Cassine albens, Neurotransmitter, Antianxiety, Antidepressant.


 
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How to Cite this Article
Pubmed Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. J Res Educ Indian Med . 2012; 18(1): 45-50.

Web Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. https://www.jreim-ayushjournal.com/?mno=191854 [Access: September 12, 2024].

AMA (American Medical Association) Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. J Res Educ Indian Med . 2012; 18(1): 45-50.


Vancouver/ICMJE Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. J Res Educ Indian Med . (2012), [cited September 12, 2024]; 18(1): 45-50.


Harvard Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA (2012) PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. J Res Educ Indian Med , 18 (1), 45-50.


Turabian Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. 2012. PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. Journal of Research and Education in Indian Medicine, 18 (1), 45-50.


Chicago Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. "PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS." Journal of Research and Education in Indian Medicine 18 (2012), 45-50.


MLA (The Modern Language Association) Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA. "PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS." Journal of Research and Education in Indian Medicine 18.1 (2012), 45-50. Print.


APA (American Psychological Association) Style

P. H. PATIL, M. B. GAGARANI, K. R. PATIL, S. J. SURANA (2012) PHARMACOLOGICAL SCREENING OF CASSINE ALBENS (RETZ.) KOSTERM (CELASTRACEAE) FOR ANTIDEPRESSANT AND ANXIOLYTIC ACTIVITY IN RODENTS. Journal of Research and Education in Indian Medicine, 18 (1), 45-50.


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