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Original Research
Online Published: 13 Jun 2015
 


PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel.


Abstract
The methanolic extract of Hemidesmus indicus Linn. (MEHI) roots were evaluated for its psychopharmacological activities in several experimental models using Swiss albino mice and Spargue dawley rats. The MEHI was found to cause significant reduction in spontaneous activity, and decreases in exploratory behavioral profiles by the Y-maze and head dip test. It also showed reduction in muscle relaxant activity by rotarod; 30° inclined screen and traction tests, as well as significantly potentiated the phenobarbitone sodium induced sleeping time in the doses examined (200, 400 and 600 mg/kg body wt.). All the results were compared with respective controls for the evaluation of significance. Keywords: Y-maze test, Head dip test, Relaxant activity, Traction tests, Tranquilizer, Hemidesmus indicus Linn., Medicinal plants, Ayurvedic medicine.


 
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How to Cite this Article
Pubmed Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. J Res Educ Indian Med . 2009; 15(1): 39-44.

Web Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. https://www.jreim-ayushjournal.com/?mno=191508 [Access: September 13, 2024].

AMA (American Medical Association) Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. J Res Educ Indian Med . 2009; 15(1): 39-44.


Vancouver/ICMJE Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. J Res Educ Indian Med . (2009), [cited September 13, 2024]; 15(1): 39-44.


Harvard Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel (2009) PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. J Res Educ Indian Med , 15 (1), 39-44.


Turabian Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. 2009. PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. Journal of Research and Education in Indian Medicine, 15 (1), 39-44.


Chicago Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. "PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER." Journal of Research and Education in Indian Medicine 15 (2009), 39-44.


MLA (The Modern Language Association) Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel. "PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER." Journal of Research and Education in Indian Medicine 15.1 (2009), 39-44. Print.


APA (American Psychological Association) Style

V.R. Chidrawar, N.J. Patel, Y.V. Ushir, K.N. Patel (2009) PRE-CLINICAL EVOLUTIONARY STUDY OF HEMIDESMUS INDICUS LINN AS MINOR TRANQUILIZER. Journal of Research and Education in Indian Medicine, 15 (1), 39-44.


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