Abstract
Background: The utilization of pesticides is increased along with green revolution in all over world including India and the percentages of utilization are continuously increasing day by day. Pesticides are well absorbs through skin, oral and respiratory mucosa and most of the population exposed during working in the industries or agriculture. People can also indirectly expose due to consumption of green vegetables, fruits etc or water which is already exposed by pesticides. Most of the pesticides like organochlorine are accumulate in human body and exist for several years, which produces adverse health effect after some exaggerated factor or after approaching a peak level. Aims and Objectives: To design the complete protocol of Ayurvedic Management for Cumulative Toxicity of Pesticides.
Material and Method: Material related to Cumulative Toxicity of Pesticides due to Bioaccumulation in human body essence has collected from research article published in index journal. Ayurvedic Text has reviewed and designed the protocol of Ayurvedic Management for Cumulative Toxicity of Pesticides.
Result and Discussion: The most of the pesticides like Organophasphorous, Organochlorine and Organocarbomate has been deposited within the cellular level as they have a lipophillic in nature and not excrete from human body completely due to more biological half life time. When these pesticides expose in human being continuous and persistently by means of occupational related direct exposure or indirect exposure by means of contaminated foods, it causes accumulation within the cellular level. When these accumulation across the permissible level, the toxicogenis is going to start along with clinical manifestation and complication which is somewhat similar to Dushee Visha (cumulative poison). The Ayurvedic Diagnostic method has developed to evaluate the Dosha-Dhatu-Srotas Vikriti (Vitiation of body element, tissue and channels) and the Protocol for Management has developed on the basis of diagnosis for detoxification of accumulated pesticide from the human body. Sudation before induced emesis and purgation by Lagenaria Siceraria (Alabu) and Milky Juice of Euphorbia nerifolia (Snuhi) with rock salt and Triphala decoction may be benefited respectively. Suitable Diet, Dushi Vishari Agad and Kashopoka Virechan Yoga play a great role after Sanshodhan (Bio Purification).
Conclusion: Cumulative toxicity may be managed by Ayurvedic Protocol using Bio-Purification and Internal Medication.

Key words: Pesticides, Cumulative Toxicity, Dushee Visha, Ayurvedic Protocol