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Review Article
Online Published: 20 Mar 2023
 


Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava

MADHAVI RAO, SAVITHA RAO, LAKSHMIPRASAD L JADHAV.


Abstract
Abstract

Introduction: Biological inheritance, the process that makes an offspring acquire or become predisposed to characteristics of its parent can be understood in terms of prakriti. The determination of prakriti is dependent on the utkata dosha during the samyoga of shukra and shonita.1 The process of genetic coding begins at fertilization, DNA replicate with each dividing cell to carry the inherited information.

Materials and methods: Construction of this article was done utilizing the concepts of Prakriti and Vikara vighata bhava stated in the Ayurveda samhitas. The basics of genetics were adopted from the available literature through books and published works.
Results: The present article provides a theoretical review of the concept of genetic predisposition, disease occurrence and variable presentation.

Discussion: Penetrance and expressivity of a particular trait is dependent on various factors like modifier genes, epigenetic factors or the environment. The non-occurrence & occurrence of diseases, get similarly affected by the presence or absence of vikara vighatakara bhava2 respectively.

Conclusion: Thus the concepts of genetics can be imbibed into the concepts of prakriti & vikara vighata bhava.

Key words: Expressivity, Penetrance, Prakriti, Vikara vighatakara bhava

Key words: Expressivity, Penetrance, Prakriti, Vikara vighatakara bhava


 
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How to Cite this Article
Pubmed Style

RAO M, RAO S, JADHAV LL. Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. J Res Educ Indian Med . Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677

Web Style

RAO M, RAO S, JADHAV LL. Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. https://www.jreim-ayushjournal.com/?mno=58685 [Access: September 12, 2024]. doi:10.5455/JREIM.82-1614158677

AMA (American Medical Association) Style

RAO M, RAO S, JADHAV LL. Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. J Res Educ Indian Med . Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677


Vancouver/ICMJE Style

RAO M, RAO S, JADHAV LL. Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. J Res Educ Indian Med , [cited September 12, 2024]; Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677


Harvard Style

RAO, M., RAO, . S. & JADHAV, . L. L. (2023) Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. J Res Educ Indian Med , Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677


Turabian Style

RAO, MADHAVI, SAVITHA RAO, and LAKSHMIPRASAD L JADHAV. 2023. Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. Journal of Research and Education in Indian Medicine, Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677


Chicago Style

RAO, MADHAVI, SAVITHA RAO, and LAKSHMIPRASAD L JADHAV. "Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava." Journal of Research and Education in Indian Medicine Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677


MLA (The Modern Language Association) Style

RAO, MADHAVI, SAVITHA RAO, and LAKSHMIPRASAD L JADHAV. "Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava." Journal of Research and Education in Indian Medicine Online First: 20 Mar, 2023. Web. 12 Sep 2024 doi:10.5455/JREIM.82-1614158677


APA (American Psychological Association) Style

RAO, M., RAO, . S. & JADHAV, . L. L. (2023) Genetic predisposition, Penetrance and Expressivity: An understanding through Prakriti and Vikara vighata bhava. Journal of Research and Education in Indian Medicine, Online First: 20 Mar, 2023. doi:10.5455/JREIM.82-1614158677


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