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Original Research
Online Published: 22 Dec 2022
 


EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS

Shweta Sandipan Paul, Karunanidhi Sharma.


Abstract
Introduction: Pudina or Mint or Meantha viridis is an important drug used in traditional systems of medicines to treat Stomachache, Dyspepsia, Indigestion, tastelessness, colic pain etc. Pudina and its distillate (Arka) has been indicated in classics to treat Chhardi (Vomiting), Ajeerna (Indigestion), Adhamaana (Flatulence), Udarshoola (Stomachache), Mandagni (Low appetite /digestive fire) and colic pain. Isolated tissue bath study is a classical and best way to evaluate the effect of any medication on smooth muscles. The present study was aimed on To evaluate the effect of Pudina Arka on isolated smooth muscle of rat ileum.
Material and methods: Sample of Pudina Arka was prepared in the Departmental Lab, PG Department of Rasashastra & Bhaishajya Kalpana, National Institute of Ayurveda, Jaipur. Isolated rat ileum was set on organ bath assembly in Tyrode solution with maintain the temperature at 37OC, Oxygen and nutrition. Contraction was induced by Acetylcholine. Then the response of Pudina Arka was observed at the dose of 0.5 ml, 1 ml, 1.5 ml and 2 ml/ 40 ml Tyrode solution.
Observations and Results: Relaxations were observed on all the doses of Pudina Arka against the contraction induced by Acetylcholine. The Effective Concentration for 50% effect (EC50) was found 0.0165 ml/ml.
Conclusion: Pudina Arka has antispasmodic or relaxant effect on smooth muscles of ileum.
.

Key words: KEYWORDS: Arq-e-Pudina, Arq-e-nana, Distillate of Mint, Arka Kalpana.


 
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How to Cite this Article
Pubmed Style

Paul SS, Sharma K. EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. J Res Educ Indian Med . Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909

Web Style

Paul SS, Sharma K. EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. https://www.jreim-ayushjournal.com/?mno=48833 [Access: September 12, 2024]. doi:10.5455/JREIM.82-1557828909

AMA (American Medical Association) Style

Paul SS, Sharma K. EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. J Res Educ Indian Med . Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909


Vancouver/ICMJE Style

Paul SS, Sharma K. EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. J Res Educ Indian Med , [cited September 12, 2024]; Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909


Harvard Style

Paul, S. S. & Sharma, . K. (0) EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. J Res Educ Indian Med , Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909


Turabian Style

Paul, Shweta Sandipan, and Karunanidhi Sharma. 0. EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. Journal of Research and Education in Indian Medicine, Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909


Chicago Style

Paul, Shweta Sandipan, and Karunanidhi Sharma. "EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS." Journal of Research and Education in Indian Medicine Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909


MLA (The Modern Language Association) Style

Paul, Shweta Sandipan, and Karunanidhi Sharma. "EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS." Journal of Research and Education in Indian Medicine Online First: 22 Dec, 2022. Web. 12 Sep 2024 doi:10.5455/JREIM.82-1557828909


APA (American Psychological Association) Style

Paul, S. S. & Sharma, . K. (0) EFFECT OF PUDINA ARKA (HYDRO DISTILLATE OF MENTHA) ON RAT ILEUM, AGAINST ACETYL CHOLINE INDUCED CONTRACTIONS. Journal of Research and Education in Indian Medicine, Online First: 22 Dec, 2022. doi:10.5455/JREIM.82-1557828909


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